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Transcriptional and Translational Regulation of Stem Cells Softcover Repri Edition
Contributor(s): Hime, Gary (Editor), Abud, Helen (Editor)
ISBN: 9402401822     ISBN-13: 9789402401820
Publisher: Springer
OUR PRICE:   $161.49  
Product Type: Paperback - Other Formats
Published: August 2016
Qty:
Temporarily out of stock - Will ship within 2 to 5 weeks
Additional Information
BISAC Categories:
- Medical | Research
- Science | Life Sciences - Cell Biology
- Science | Life Sciences - Molecular Biology
Dewey: 571.6
Series: Advances in Experimental Medicine and Biology
Physical Information: 371 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes - achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic - (1) illustrating the general principles outlined above through a series of different stem cell examples - embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.