| Toxicogenomics in Predictive Carcinogenicity Contributor(s): Thomas, Russell S. (Editor), Waters, Michael D. (Editor) |
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ISBN: 1782621628 ISBN-13: 9781782621621 Publisher: Royal Society of Chemistry OUR PRICE: $238.45 Product Type: Hardcover - Other Formats Published: July 2016 |
| Additional Information |
| BISAC Categories: - Medical | Oncology - General - Science | Life Sciences - Genetics & Genomics - Medical | Toxicology |
| LCCN: 2016449231 |
| Series: Issues in Toxicology |
| Physical Information: 1.3" H x 6.4" W x 9.3" (2.00 lbs) 524 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Toxicogenomics in Predictive Carcinogenicity describes toxicogenomics methods in predictive carcinogenicity testing, mode of action and safety evaluation, and cancer risk assessment. It illustrates these methods using case studies that have yielded significant new information on compounds and classes of compounds that have proven difficult to evaluate using conventional methods alone. This book additionally covers current and potential toxicogenomic research using stem cells as well as new bioinformatics methods for drug discovery and environmental toxicology.The information is needed because it has not previously been available. With the increasing complexity of research in mode of action investigations it is important to gain a better understand of approaches to data integration and health risk assessment. Furthermore, it is essential to consider how novel test systems and newer methods and approaches may be used in future to gain a better understanding of mechanisms. The proposed publication will provide details of chemical case studies not available in previous volumes and will demonstrate how various data is assembled and integrated to arrive at an informed assessment of chemical safety and human health risk. It will be the most current volume which comprehensively covers the subject. This publication is an indispensable tool for postgraduates, academics and industrialists working in biochemistry, genomics, carcinogenesis, pathology, pharmaceuticals, food technology, bioinformatics, risk assessment and environmental toxicology. Societies: American Association for Cancer Research AACR (http: //www.aacr.org/) Environmental Mutagenesis and Genomics Society (http: //www.emgs/org) International Association of Environmental Mutagen Societies (http: //www.iaems/org) International Union of Toxicology (http: //www.iutox.org/) Society of Toxicology (http: //www.toxicology.org/) Journals for reviews: Cancer Research Mutation Research Toxicology Research Toxicology and Applied Pharmacology Regulatory Toxicology and Pharmacology Toxicology Toxicology Letters Critical Reviews in Toxicology Archives of Toxicology Pharmacology & Toxicology Fundamental and Applied Toxicology Toxicologic Pathology Clinical Toxicology Human and Experimental Toxicology International Journal of Toxicology Toxicology and Industrial Health Drug and Chemical Toxicology Drug safety Journal of Toxicology Toxicological Sciences Websites: American Association for Cancer Research AACR (http: //www.aacr.org/) Environmental Mutagenesis and Genomics Society (http: //www.emgs/org) International Association of Environmental Mutagen Societies (http: //www.iaems/org) International Union of Toxicology (http: //www.iutox.org/) Society of Toxicology (http: //www.toxicology.org/) Cross-promote with the textbook Fundamental Toxicology |
Contributor Bio(s): Waters, Michael D.: - Michael D. Waters, holds a Ph.D. in Biochemistry from the University of North Carolina School of Medicine at Chapel Hill and a B.S. in Pre-medicine (Chemistry and Biology) from Davidson College. He is a former government scientist with more than 35 years of experience in research and research management positions at EPA and NIH/NIEHS and six years of private sector experience as Chief Scientific Officer at Integrated Laboratory Systems, Inc. His research interests have centered on the evaluation of chemically-induced mutations and altered molecular expression in the etiology of genetic disease. He is a widely-published scientist having published well over 100 peer-reviewed in authoritative international scientific journals. He has edited Mutation Research-Reviews for nearly 20 years and has held adjunct professorships at both the University of North Carolina and at Duke University for many years. He served as President of both the Environmental Mutagen Society and the International Association of Environmental Mutagen Societies (now the Environmental Mutagenesis and Genomics Society and the International Association of Environmental Mutagenesis and Genomics Societies, with more than seven thousand members worldwide). The databases he has developed and a number of his publications are recognized as important advances that have significantly impacted the fields of genetic toxicology, carcinogenesis, toxicogenomics, and risk assessment. |