| Computational Methods for Processing and Analysis of Biological Pathways 2017 Edition Contributor(s): Bezerianos, Anastasios (Author), Dragomir, Andrei (Author), Balomenos, Panos (Author) |
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ISBN: 3319538675 ISBN-13: 9783319538679 Publisher: Springer OUR PRICE: $52.24 Product Type: Paperback Published: June 2017 |
| Additional Information |
| BISAC Categories: - Computers | Computer Science - Science | Life Sciences - Biology - Science | Research & Methodology |
| Dewey: 570 |
| Series: Springerbriefs in Computer Science |
| Physical Information: 87 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways. |