| Epigenetic Mechanisms in Cancer: Volume 3 Contributor(s): Saldanha, Sabita (Editor) |
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ISBN: 0128095520 ISBN-13: 9780128095522 Publisher: Academic Press OUR PRICE: $142.50 Product Type: Hardcover Published: November 2017 |
| Additional Information |
| BISAC Categories: - Medical | Genetics - Science | Life Sciences - Genetics & Genomics - Science | Life Sciences - Molecular Biology |
| Series: Translational Epigenetics |
| Physical Information: 392 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes. |
