Membrane Permeability: 100 Years Since Ernest Overton: Volume 48 Contributor(s): Benos, Dale J. (Editor), Deamer, David W., Kleinzeller, Arnost |
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ISBN: 0121533484 ISBN-13: 9780121533489 Publisher: Academic Press OUR PRICE: $217.80 Product Type: Hardcover - Other Formats Published: May 1999 Annotation: Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Key Features * Provides an historical perspective of Overton's contributions to the theory of narcosis * Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion |
Additional Information |
BISAC Categories: - Science | Life Sciences - Cell Biology - Science | Life Sciences - Biophysics - Science | Life Sciences - Biochemistry |
Dewey: 574.875 |
Series: Current Topics in Membranes |
Physical Information: 0.97" H x 6.17" W x 9.27" (1.47 lbs) 423 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. |