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Systemic Treatment of Prostate Cancer
Contributor(s): Horwich, Alan (Editor)
ISBN: 0199561427     ISBN-13: 9780199561421
Publisher: Oxford University Press, USA
OUR PRICE:   $38.94  
Product Type: Paperback - Other Formats
Published: April 2010
Qty:
Temporarily out of stock - Will ship within 2 to 5 weeks
Additional Information
BISAC Categories:
- Medical | Oncology - General
Series: Oxford Oncology Library
Physical Information: 0.23" H x 5.95" W x 7.06" (0.24 lbs) 104 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple
sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay of endocrine therapy in this group of patients, though anti-androgens, oestrogens, and corticosteroids can also
cause remissions. In recent years effective and well-tolerated chemotherapy regimens have been developed and evaluated. Docetaxel has an established role, and a range of biologically-targeted agents are in development.

The dominant pattern of metastatic spread is to the axial skeleton and most symptomatic care is directed to palliation of bone pain. The role of bisphosphonates remains controversial, but bone-directed isotopes such as Strontium-89 are effective.

Part of the Oxford Oncology Library, this pocketbook summarizes the up-to-date information on the use of systemic therapies in the management of prostate cancer (early stage, metastatic disease, and treatment of biochemical recurrence). With contributions from leading oncologists from both Europe
and the USA, the book provides a practical guide to the range of endocrine and cytotoxic therapies currently available to clinicians, as well as to other palliative anticancer strategies, and will be valuable to all health professionals involved in the management of patients with prostate cancer.