| The Construction of Analogy-Based Research Programs: The Lock-And-Key Analogy in 20th Century Biochemistry Contributor(s): Mertens, Rebecca (Author) |
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ISBN: 3837644421 ISBN-13: 9783837644425 Publisher: Transcript Publishing OUR PRICE: $39.60 Product Type: Paperback Published: September 2019 |
| Additional Information |
| BISAC Categories: - Philosophy | Epistemology - Science | History |
| Series: Science Studies |
| Physical Information: 0.7" H x 5.8" W x 8.9" (0.80 lbs) 230 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modeling. |
