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We can look at the Universe from different points of view. This research was built based on a modern physics and design point of view to be as comprehensible as possible, more specifically on how we, humans, observe time and space, creating our own views of it, depending on our observations and with machines that we make, to help us to understand the Universe further. We use the latest tools and knowledge to go beyond our biological limits and achieve control of our bodies, minds, and surroundings. The merging of human and machine, natural and artificial, that we are starting to witness is something to which we must pay attention. That merging will change, probably much faster than we anticipate, what it means to be human and consequently our humanity. In this regard, a manifesto was presented with the intent to alert designers to the real needs of humans that somehow have been neglected as well as the possible consequences on humanity by blindly using new technological advancements on products. With a similar purpose, a new design approach called H+design was presented that considers more the social needs which make us human. Its main purpose is to help designers to be able to create the next human nature by predicting more accurately the future possibilities of technology and its possible uses without disregarding the human needs. We should strive to become better, to improve ourselves, without losing track of what it means to be human, without losing our humanity.